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Ridiculed, 345 pounds, suicidal – heavyweight now chasing family 40-0

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Joseph Mesi Jr. transformation image showing the heavyweight prospect at 345 pounds before beginning his boxing journey alongside a current promotional poster highlighting his 3-0 professional record and family link to former undefeated heavyweight Joe Mesi.

“They laughed when I said I was going to be a professional boxer.” – these were the words written by potential heavyweight fighter Joseph Mesi Jr. earlier this year when he recalled his journey into the professional ranks.

The son of former heavyweight fighter Joe Mesi also revealed that he once weighed 345 pounds and struggled with depression and suicidal thoughts before turning his life around.

Today Mesi Jr. he is 3-0 as a professional and is one win away from helping his family to a perfect overall record of 40-0.

Heavyweight father and son

The elder Mesi retired from boxing in 2007 with an undefeated record of 36-0, after a career that once seemed destined for world title contention.

As World Boxing News has previously covered in its look back on Mesi’s career, the Buffalo heavyweight became one of boxing’s greatest stories when health problems cut low his career just as he was on the brink of contention.

Despite never getting a chance to fight for a world title, Mesi came out perfect with 29 knockouts and victories over names like Monte Barrett, DaVarryl Williamson and former cruiserweight champion Vassiliy Jirov.

For years, the 36-0 mark remained untouched. Now it has a second chapter.

A perfect 40-0

Joseph Mesi Jr. he made his professional debut in October 2024 and already has a 3-0 record and two wins after the break.

The 31-year-old heavyweight will return on July 14 in Rochester against an unknown opponent.

A victory would raise the combined record of father and son to 40-0.

Not many boxing families can boast such an undefeated record in the heavyweight division.

Many sons followed in the footsteps of notable fathers and joined the sport. Few did so, carrying the ‘0’ which remained intact for almost two decades before being given the opportunity to continue doing so.

Different meaning

The younger Mesi’s post on social media looks completely different today.

The same man who claims he was ridiculed for wanting to become a professional boxer has already overcome obstacles far greater than skepticism.

Mesi Jr. he had previously spoken about weighing 345 pounds and struggling with depression and suicidal thoughts before finding direction in boxing.

After three wins in his career, he is no longer trying to prove that he belongs in the sport.

Instead, he’s trying to extend a family record that seemed finished when his father retired.

One more win would take Mesis to a perfect 40-0.


About the author

Phil Jay is the editor-in-chief of World Boxing News (WBN) and a boxing veteran with over 15 years of experience. Read the full biography.

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Anthony Joshua vs Tyson Fury: Live London Press Conference Showdown

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"Anthony Joshua vs Tyson Fury: Live London Press Conference Showdown"

The long-awaited, all-British heavyweight blockbuster between Tyson Fury and Anthony Joshua is officially set for December 11 at the Principality Stadium in Cardiff.

Backed by Saudi powerbroker Turki Alalshikh, the defining clash will see both men pocket a career-high purse and settle the debate – to a degree – of this generation’s best UK heavyweight.

After more than a decade of false starts and fractured negotiations, the two former heavyweight champions will finally settle their rivalry in what promises to be the biggest commercial event in British boxing history. Broadcast rights have been secured by Netflix for a global audience and Filipino icon Manny Pacquiao may appear on the undercard, despite turning 49 one week after the event.

Crucially, Joshua’s camp held firm during negotiations to ensure the bout remained on domestic soil. Despite the potential for more lucrative offers overseas, ‘AJ’ refused to budge on the location, and the pair meet today in London to make it official.

Fans can watch live via the stream below, with the proceedings expected to kick off at 6 PM – though delays and gamesmanship may be a factor.